The cellulose department has prepared safety data sheets sds for our major. Contact with the skin is not expected to cause prolonged or significant irritation. Never give anything by mouth to an unconscious person. Pdf bookmark sample page 1 of 4 pdf bookmark sample sample date. Methocel e4m hypromellose 2910 usp sds preparation date 07032017 page 1 of 8. Transfer a quantity of hypromellose w u weight of hypromellose, calculated on the equivalent to 10g of solids, calculated on the dried dried basis, taken for the sample solution basis, to a tared, widemouth centrifuge bottle, and mg add hot water to obtain a total weight of the sample. Accelio present applied technology created and tested using. Review the material safety data sheet msds for this material prior to working with this chemical. Aquasolve hypromellose acetate succinate hpmcas gradea weight average molecular weight nominal viscosity mpas b l 114,700 2. Add the sample solution to exactly 50ml of hypromellose water in a beaker. Safety data sheet gasoline, unleaded sample please note. Material safety data sheet carboxymethyl cellulose, sodium. For a highquality, custom msds binder, look to binders, inc.
Hydroxypropylmethyl cellulose, hydroxypropylmethylcellulose 2910. Transfer a quantity of hypromellose 3 in the portion of hypromellose taken. Do not use combustible materials, such as saw dust. Material safety data sheet bnz materials industrial. Affinisol hpmcas for spraydried dispersion sdd hpmcas to the solution to give a clear to slightly opaque final solution with 25 wt% api to 75 wt% affinisol hpmcas ratio. Msds examples sds sheets msds authoring services inc. Add the sample solution to exactly 50 ml of water in a beaker. Calculate the percentage of methoxy och sample solution.
A liquid is typically considered a nonconductive, static accumulator if its. Methocel k100m premium hydroxypropyl methylcellulose. Before films were prepared, dissolved gas was removed from the solution by placing the sample. Effect of formulation conditions on hypromellose performance properties in films used for capsules and tablet coatings. You can obtain samples by calling one of the numbers listed on the back cover of this. Pfizer inc believes that the information contained in this material safety data sheet is accurate, and while it is provided in good faith, it is without warranty of any kind, expressed or implied. Handling and storage protect container from physical. This information is to the best of our knowledge is considered accurate. Our sturdy, wellmade professional binders, along with index tab dividers, are sure to keep all your information safe. Sigmaaldrich offers a number of hypromellose products. Aquasolve hpmcas for pharmaceutical applications is a cellulosic polymer with four substituents randomly substituted on the available hydroxyl groups with the following mass. Hypromellose has a physicalchemical action and leads to, in an aqueous solution, a reduced surface tension as well as an increased level of viscosity. Examples safety data sheet sdsmsds here you can see examples of safety data sheets in some of the various languages we handle. Benecel methylcellulose and hypromellose hydroxypropyl methylcellulose or hpmc are.
Safety data sheet section 1 identification of the substancemixture and of the companyundertaking. Alert a doctor if you have ever had any unusual or allergic reaction to hypromellose. Other companies are charging thousands of dollars to set up accounts and give you. Stir the solution on a magnetic stirrerhot plate, portions of this monograph that are national usp text, and and begin heating at a rate of 25min. Generic safety data sheet sds cover sheet sample preparation kit ki3010 component description ch 2003 alkylation solution ch 2004 reduction stock solution so. Stage 6 harmonization official december 1, 2016 hypromellose1 analysis. Similar results were observed when groups of 20 rats were fed a diet of 2, 10 and 25% for 30 days. Certificate of analysis coa specification sheet pdf. Examples safety data sheet sds msds here you can see examples of safety data sheets in some of the various languages we handle. Weight loss, early deaths and severe diarrhea was observed only at the 25% level. All spectrum chemical usp products are manufactured, packaged and.
Methocel cellulose ethers include methylcellulose mc or hydroxypropyl methylcellulose hpmc polymers with solubilities ranging from watersoluble to organosoluble. Hypromellose meets usp testing specifications sigmaaldrich. The viscosity promoting properties of hypromellose prolong the retention time and improve adhesion of synthetic tears to the cornea and conjunctiva. Material safety data sheet croscarmellose sodium page 3 of 5 section 8 exposure controls personal protection engineering controls. Msds authoring services specialize in msds writing, creation, development and authoring. Not expected to be harmful to internal organs if absorbed through the skin. The information in this msds is written in good faith, but no warranty is given, to what is expressed or implied. Material safety data sheet carboxymethyl cellulose, sodium salt, average mw 90. Our core businesses include film coatings, modified release.
Rather than being abused, hypromellose is included in oral formulations of ms contin, oxycontin, opana er, and others. Visit the reach website for more information regarding dow and reach. In two dogs fed a diet containing 25 or 50 g hpmc daily for 30 days only the dog fed 50g experienced weight loss, diarrhea and anemia. Contents page preface designation and structural formula of hpmcp designation, admissions to compendia, chemical name trade name. Sample quantities of methocel products are available free of charge for your developmental work. Upper layer of the standard solution and the samples having a viscosity type of less than 600 mpa sample solution s. Relying on the advanced and refined testing equipment, as well as the ambitious spirit to provide the best products in the worl hypromsllose. Affinisol hpmcas for spraydried dispersion sdd solving. Methocel e4m hypromellose 2910 usp encore scientific. We work hard to ensure that we are fully uptodate with regulations, and make sure to incorporate changes as soon as they occur, so that you do not risk having outofdate safety data sheets. Give the person a glass of water or milk to drink and get immediate medical attention. Being a part of the shinetsu group, we unite innovation and tradition. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Formerly known as material safety data sheets, phac now refers to them as pathogen safety data sheets or psdss.
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